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欧盟评估一种内切-1,4-β-木聚糖酶的安全性和有效性

放大字体  缩小字体 时间:2019-11-12 10:36 来源:食品伙伴网 作者: 可心   
核心提示:2019年11月8日,据欧盟食品安全局(EFSA)消息,应欧盟委员会要求,欧盟动物饲料添加剂和产品(FEEDAP)研究小组就Belfeed B MP/ML(内切-β-1,4木聚糖酶(endo‐1,4‐β‐xylanase))的安全性和有效性发表科学意见。
  食品伙伴网讯  2019年11月8日,据欧盟食品安全局EFSA)消息,应欧盟委员会要求,欧盟动物饲料添加剂和产品(FEEDAP)研究小组就Belfeed B MP/ML(内切-β-1,4木聚糖酶(endo‐1,4‐β‐xylanase))的安全性和有效性发表科学意见。
 
  据了解,该添加剂含有的内切-1,4-β-木聚糖酶是由一种转基因枯草芽孢杆菌(Bacillus subtilis)生产的,并在欧盟被授权作为家禽育肥饲料添加剂、断奶仔猪饲料添加剂和猪育肥饲料添加剂。
 
  部分原文报道如下:
 
  Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Belfeed B MP/ML as a feed additive for sows in order to have benefits in piglets and for all porcine species. This additive contains endo‐1,4‐β‐xylanase produced by a genetically modified strain of Bacillus subtilis and it is authorised in the European unio as a feed additive for poultry for fattening, weaned piglets and pigs for fattening. The applicant requested the extension of use of the additive to sows in order to have benefits in piglets and to all porcine species at any developmental stage at 10 IU/kg feed. The FEEDAP Panel concluded that there are no concerns for consumer safety and no risks for the environment are expected from the use of Belfeed B MP/ML in all Suidae species. The additive is not irritant for skin or eye but it should be considered a potential respiratory sensitiser for the users, the Panel could not conclude on the potential of the additive as a potential dermal sensitiser. Considering the results from a tolerance trial done in weaned piglets, those in a subchronic oral toxicity study and the nature/origin of the product under assessment the Panel concluded that the additive is safe for all porcine species at any developmental stage. The data previously assessed in piglets and pigs for fattening allowed to conclude that the additive is efficacious at 10 IU/kg feed in suckling piglets and all Suidae species from suckling to slaughter. The data submitted to support the efficacy for sows was considered insufficient and therefore the Panel could not conclude on the efficacy in sows.
 
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日期:2019-11-12
 
 
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